The 183rd prohibition is that we are forbidden from eating the sciatic nerve (gid ha'nasheh).
The source of this prohibition is G‑d's statement,1 "The Jewish people therefore do not eat the sciatic nerve to this very day."
One who eats the entire nerve, even if it is minute in size, or one who eats a kezayis [even if it is not the entire nerve] receives lashes.
