The 48th prohibition is that we are forbidden from making a covenant with the heretics, i.e. the seven nations,1 and to allow them to remain2 in their heresy.

The source of this commandment is G‑d's statement (exalted be He),3 "Do not make a covenant with them."

We have already explained in Positive Commandment 187 that the war against the seven nations and everything connected with them can be counted [in the 613 commandments], and are not placed in the category of commandments which do not apply for all generations.4