At three weeks, the blastocyst, or developing embryo, is looking for a spot to implant in the uterus. Early formation of the central nervous system, backbone, and spinal column has begun. The gastrointestinal system has also begun to develop with the kidneys, liver, and intestines forming. The heart has begun to form.

At four weeks hormones produced by the embryo stop the mother's menstrual cycle.

The embryo's tiny heart begins to beat by day twenty-one from conception. The brain has developed into 5 areas and some cranial nerves are visible. Arm and leg buds are visible and the formation of the eyes, lips, and nose has begun. The spinal cord grows faster than the rest of the body giving a tail like appearance which disappears as the embryo continues to grow. The placenta begins to provide nourishment for the embryo.